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Application for Verification of Data Accuracy in the SAP HCM Module
Kolb, Jakub ; Očenášek, Pavel (referee) ; Bartík, Vladimír (advisor)
Main goal of this bachelors thesis is to show issue of data checking in system SAP. Since this system is extensive, it is nearly impossible to control the data manually. In this bachelor thesis I am describing particular proposals for improving the processes including their use in practice. This bachelor thesis is divided into three parts. In first part is mentioned necessary theory used for implementing application for data checking. Next I describe particular important data dividing with proposal of class and domain diagram. In last part of thesis I pay attention to realization and programming itself in programming language ABAP.
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Application for Verification of Data Accuracy in the SAP HCM Module
Kolb, Jakub ; Očenášek, Pavel (referee) ; Bartík, Vladimír (advisor)
Main goal of this bachelors thesis is to show issue of data checking in system SAP. Since this system is extensive, it is nearly impossible to control the data manually. In this bachelor thesis I am describing particular proposals for improving the processes including their use in practice. This bachelor thesis is divided into three parts. In first part is mentioned necessary theory used for implementing application for data checking. Next I describe particular important data dividing with proposal of class and domain diagram. In last part of thesis I pay attention to realization and programming itself in programming language ABAP.
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Host factors involved in Rous Sarcoma Virus replication
Štafl, Kryštof ; Svoboda, Jan (advisor) ; Horníková, Lenka (referee)
Rous sarcoma virus (RSV) takes a place of honor among retroviruses. Research of RSV allows us to uncover the secret of the origin and evolution of life, the mechanisms of tumorigenesis and the interaction between viruses and their hosts. Viruses are not able to replicate themselves without host cells. They exploit a number of cellular pathways and factors and they can reprogram the cells to produce great amounts of viral progeny. They exert pressure on their host that leads to developement of new types of cellular proteins, which then results in resistance of the cells. This thesis focuses on the host factors involved in the RSV replication cycle. It summarizes the current knowledge about the replication cycle of retroviruses and the host factors that are necessary for productive infection: cellular receptors, endocytic and secretory pathways, nuclear transport, proteosynthesis, replication of proviruses and its stimulation. The restriction mechanisms of cells are also taken into account. The current knowledge about RSV is compared with facts on mammalian retroviruses and gaps in research are highlighted. The influence of the host cell factor absence, host specificity and cellular permissiveness are correlated and discussed.
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